Distension and pain in the upper fossa of the stomach, which is the upper part of the stomach close to the heart, may be mainly related to several factors such as improper diet, gastrointestinal disorders and cardiovascular diseases. It is recommended to seek medical attention early and give reasonable treatment. Common causes and treatment 1, improper diet: when eating too much greasy, hard, spicy and irritating food that is not easy to digest, it will make the food stagnate in the stomach can not be digested in time, resulting in indigestion and easily cause stomach discomfort. Generally, the symptoms can be relieved by adjusting the diet or promoting gastrointestinal dynamics through appropriate application of domperidone, stomachic elimination tablets, etc.; 2. Gastrointestinal diseases: Gastritis, gastroesophageal reflux, tumors and other digestive system diseases can lead to gastrointestinal dynamics disorder, digestive tract obstruction, slowed peristalsis, and stomach distension and pain. The diagnosis can be clarified by gastroscopy, and under the guidance of the doctor, Mosapride can be applied to promote gastrointestinal dynamics; omeprazole can neutralize stomach acid and reduce the feeling of stomach distension and pain. In addition, the presence of H. pylori infection should be considered, and amoxicillin, clarithromycin, omeprazole and colloidal bismuth can be applied for combined treatment; 3, cardiovascular diseases: coronary atherosclerotic heart disease, acute myocardial infarction, coronary artery disease and other heart diseases, due to myocardial ischemia can appear in the precordial region, posterior back and epigastric discomfort and other symptoms. The diagnosis should be made at the hospital through differential examination and timely treatment through medication or surgery to avoid delaying the disease and endangering life. Patients with upper stomach fossa discomfort should pay attention to their diet and eat light, easy-to-digest food. In addition, regular work and rest, avoid staying up late to reduce the damage to the heart.