Ankylosing spondylitis is ankylosing spondylitis. The cost of biologics for the treatment of ankylosing spondylitis varies depending on the drug, such as etanercept, adalimumab, infliximab, etc., which are priced at about 1,000 to 3,000 yuan, 7,000 to 8,500 yuan, and 8,000 to 13,000 yuan. 1. Etanercept: It can be used for the treatment of ankylosing spondylitis, and can be combined with methotrexate for treatment if necessary. It is mostly used in adult patients with severe active ankylosing spondylitis when conventional treatment fails, and costs around one thousand to three thousand dollars. 2. Adalimumab: Adalimumab can improve the signs and symptoms of ankylosing spondylitis and is usually priced at around 7,000 to 8,500 dollars. 3. infliximab: infliximab can be used in the treatment of Crohn’s disease, rheumatoid arthritis, ankylosing spondylitis and other diseases, and its price is usually around eight thousand to thirteen thousand dollars. Due to the different drugs, its treatment cost also varies, and it is recommended to take the actual situation into account. Patients can choose the appropriate biological agents for treatment under the guidance of a professional doctor, according to their own situation, the specific cost of the actual situation shall prevail, it is recommended that patients with ankylosing spondylitis timely consultation, standardized diagnosis and treatment in accordance with the doctor’s instructions, in order to avoid delaying the condition.