1, novel coronavirus concept The Chinese CDC has successfully isolated China’s first novel coronavirus strain Coronaviruses are a large class of viruses known to cause disease, with patients exhibiting different clinical symptoms ranging from the common cold to severe lung infections, such as Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS). The novel coronavirus 2019-nCoV found in Wuhan is a novel coronavirus that has not been found in humans before. 2. Characteristics of novel coronavirus The novel coronavirus belongs to the genus β. It has an envelope, round or oval particles, often polymorphic, with a diameter of 60-140 nm. The current study showed more than 85% homology with bat SARS-like coronavirus (bat-SL-CoVZC45). When isolated and cultured in vitro, 2019-nCoV was found in human respiratory epithelial cells in about 96 hours, while it took about 6 days to isolate and culture in Vero E6 and Huh-7 cell lines. Much of the knowledge of the physicochemical properties of coronaviruses comes from studies of SARS-CoV and MERS-CoV. The virus is sensitive to ultraviolet light and heat, and lipid solvents such as 56°C for 30 minutes, ether, 75% ethanol, chlorinated disinfectants, peroxyacetic acid and chloroform can effectively inactivate the virus, while chlorhexidine cannot effectively inactivate the virus. 3, the new coronavirus can be transmitted from person to person According to the current evidence, it can be determined that the new coronavirus can be sustained human-to-human transmission. The main transmission routes identified so far are respiratory droplet transmission (sneezing, coughing, etc.) and contact transmission (picking the nose and rubbing the eyes with the hand that has been in contact with the virus, etc.). 4, the new coronavirus can be infected with which groups of people For the new coronavirus, the population is generally susceptible. It can occur in both immunocompromised and immunocompetent people, and is related to the amount of exposure to the virus. If exposed to a large amount of virus at one time, the disease can occur even in immunocompetent people. The disease progresses relatively faster and is more severe in immunocompromised populations, such as the elderly, pregnant women, or those with liver or kidney dysfunction. Whether or not a population is infected depends largely on exposure; it is not the case that those who are more resistant are at lower risk of infection. Children have less exposure and are less likely to be infected; the same exposure results in a greater chance of infection in older people, people with chronic diseases, and people with poor resistance. Content source: Dr. You Lai Reference Chinese Center for Disease Control and Prevention (CDC) “Public Protection Guide for Pneumonia with Novel Coronavirus Infection” Hubei Science and Technology Press “Novel Coronavirus Pneumonia Prevention Manual