Toe seam ulcers may be due to the feet being in a humid environment for a long time, or they may be a symptom of tinea pedis, eczema and other diseases. 1. When the foot has been immersed in water for a long time or is often in a humid, hot and stuffy environment, it can lead to the stratum corneum absorbing a lot of water, and the skin of the foot swells and turns white. Friction between the toes can lead to ulceration of the fragile skin, which can be gradually relieved by keeping the feet dry. 2. Tinea pedis can occur when the skin of the foot is infected by fungi, in which macerated tinea pedis is manifested as erosion between the toes, maceration and whitening, which can be treated with antifungal therapy, such as itraconazole, fluconazole, and so on. 3. Eczema is a chronic inflammatory disease that can involve all parts of the body, and when it occurs in the foot, it is foot eczema. Acute stage can be manifested as erythema on the basis of small blisters, due to intense itching, often due to scratching to form vesicles, oozing, etc., can be used locally 3% boric acid solution, zinc oxide oil and other drugs. The above are some of the reasons for the toe seam ulcers, the specific causes are recommended to consult a doctor in time to find out, the use of medication need to be guided by a doctor.