There is no western medicine for lowering creatinine. Commonly used drugs to reduce creatinine, most of them are proprietary Chinese medicines, such as urethane particles, renal failure capsule. 1. Uremic acid particles: Uremic acid particles are used in chronic renal failure and other diseases, the effect is to pass the internal organs and reduce turbidity, strengthen the spleen and diuresis, activate blood circulation and remove blood stasis (to promote blood circulation and eliminate blood stasis in the body), etc., which can help to reduce creatinine, urea nitrogen, and stabilize the renal function. 2. Renal failure capsule: it can help reduce creatinine, but there are many adverse reactions, such as nausea, vomiting, abdominal pain, diarrhea, increased frequency of bowel movements, rash, itching, etc. It is forbidden for pregnant women and people with bleeding tendency. If creatinine is elevated, the patient should consult a doctor in time, under the guidance of the doctor according to the main evidence of the use of drugs, on time and according to the dosage. The role of drugs to reduce creatinine is very limited, clinically the most effective way to reduce creatinine is to take renal replacement therapy, the specific how to choose should be regular hospital visits, the doctor to assess the condition, to take the appropriate diagnosis and treatment program.