Stomach pain without acid reflux may be caused by acute or chronic gastritis or gastric or duodenal ulcers, etc. Symptoms can be relieved by adjusting daily eating habits and medication. 1. Acute and chronic gastritis: It is recommended to have a light diet, avoid stimulating and rough food, and avoid drinking too much coffee, large amounts of alcohol and long-term smoking. Medications can apply proton pump inhibitors, such as omeprazole, rabeprazole, etc. to inhibit gastric acid and relieve pain; gastric mucosal protectors, such as magnesium aluminum carbonate chewable tablets, teprenone; gastric stimulants, such as domperidone, mosapride and so on. 2. Gastric and duodenal ulcers: quit smoking and drinking, avoid strenuous exercise, avoid stimulating food, and pay attention to rest. Drug therapy can be applied to acid inhibitors such as omeprazole, rabeprazole, ranitidine, etc. to relieve symptoms and heal ulcers; it can also be combined with gastric mucosal protective agents such as aluminum sulfate. If the stomach pain persists without obvious relief, you should go to the hospital in time, clarify the cause of the disease with the help of the doctor, and carry out standardized treatment for the cause of the disease.