If the patient has no previous history of H. pylori infection, there is no H. pylori in the stomach after distal gastrectomy; if the patient has a previous H. pylori infection, H. pylori is usually still present after distal gastrectomy. After distal gastrectomy, the duodenum will compensate for part of the function of the stomach. H. pylori is mainly parasitized in the pyloric part of the stomach, but it can also be present in other parts of the stomach and the duodenum, and this bacterium can easily lead to gastric and duodenal ulcers and gastric erosion. Anti-Helicobacter pylori treatment is mainly gastric quadruple drugs, i.e. 1 PPI + 2 antibiotics and 1 bismuth agent, such as omeprazole, amoxicillin, clarithromycin, bismuth potassium citrate, etc., with a course of 10 to 14 days. If the patient is doubtful about whether there is H. pylori infection after the operation, he/she can go to the hospital for relevant examination and decide whether he/she wants anti-H. pylori treatment according to the examination result.