Ankylosing spondylitis may be passed on to grandchildren.
Ankylosing spondylitis is a polygenic disease, and the chance of developing ankylosing spondylitis in the offspring is high. In addition, apart from genetic factors, acquired environmental factors may also lead to the development of ankylosing spondylitis disease. Therefore, ankylosing spondylitis may be passed on to grandchildren.
If a first-degree relative suffers from ankylosing spondylitis, the probability of a grandchild developing the disease is correspondingly higher. If the number of people affected by the disease in the family is relatively large, the probability of the relative being at risk of recurrence is elevated. It is now believed that the more severe the symptoms of ankylosing spondylitis, the higher the risk of recurrence in relatives, and that women are more likely to pass on the disease to their children than men.
Patients with ankylosing spondylitis are advised to go to the rheumatology and immunology department or the reproduction department of a regular hospital for detailed consultation.