Wool picking can be harmful if not done properly and can cause skin infections, common side effects include skin scarring and more. Wool picking is a kind of folk therapy, also called wool picking furuncle. It is believed that wind, cold, dampness and other evils accumulated on the body surface due to various reasons will gather under the dermis to form the so-called wool furuncle. The picking of wool can promote the discharge of toxins in the body, so that the meridians and channels can be cleared, and achieve the effect of treating diseases. 1. Harm: If this operation is not thoroughly sterilized, etc., it will easily cause skin infection, redness, swelling, heat and pain, or even bigger furuncles (mostly occurring on the limbs or face, with small shapes and deep roots, as hard as nails). 2. Skin scarring: the process of picking wool will inevitably damage the skin, but if the operation is improper damage is too heavy, it will lead to fibrous hyperplasia of the local skin, the formation of scarring, which affects the aesthetics. Treatment of wool picking this folk therapy should pay attention to evidence-based view, consult a professional physician’s opinion, to prevent adverse reactions.