The symptoms of pain all over the body in patients with brain infarction are not necessarily related to the brain infarction. If it appears after a brain infarction, consider that the patient may be infarcted at the site of the infarction, in the thalamic sensory center, and the patient will have thalamic pain. The main manifestation is the abnormal sensation of the contralateral limb of the thalamic blockage, such as pain, or stabbing or cutting pain. When generalized pain occurs after a brain infarction, the patient’s emotion is considered to be related. After a brain infarction, the patient develops post-stroke anxiety and depression, which can manifest as many somatization symptoms. Patients may show pain and discomfort in the limbs, as well as poor sleep at night, and may show panic and sweating, as well as dizziness and heavy head. For this situation, it is recommended to give the patient anti-anxiety medication, such as oral Dextran, and flupirtine melitrexin tablets.