High blood pressure may cause generalized edema, considering that there is hypertension combined with heart failure, kidney damage, but also may be considered related to edema caused by taking certain drugs. 1. Combined heart failure: patients with hypertension usually do not pay attention to diet or medication, resulting in persistent elevation of blood pressure, may be combined with other diseases, such as combined coronary heart disease leading to heart failure, may cause generalized edema. 2. Combined renal damage: persistent elevation of blood pressure, resulting in renal damage or combined renal disease, prone to water and sodium retention, resulting in generalized edema. 3. Drug factors: some hypertensive patients taking long-term antihypertensive drugs, such as felodipine, nifedipine, edema may occur, which is considered to be related to the long-term use of drugs. It is recommended to pay close attention to the changes of blood pressure, go to the cardiovascular department of the hospital if necessary, or combine with the doctor’s advice to change other drugs.