Organ failure is very distressing and manifests itself in different ways for different organs. For example, the most important manifestation of heart failure is dyspnea, which can be characterized by significant breathlessness after activity or when lying down. Some patients also wake up at night, and usually have to sit up to feel comfortable. Patients with kidney failure may also experience anuria, fatigue, and swelling. With multiple organ failure, basic vital signs may not be maintained for a short period of time. If there is a rapid drop in blood pressure, heart rate, and purple skin, lips and mouth, the patient must be in great pain during the process. In addition, it is necessary to determine whether the organ failure is acute or chronic. If the onset of the disease is very rapid and the disease progresses rapidly, it will soon lead to a malignant adverse event, and the patient will experience a sudden death, and the relative suffering of the patient will be reduced. In chronic organ failure, the suffering of the patient is also more pronounced and is usually a long-term manifestation with slowly increasing involvement.