Possible causes of infertility with normal sperm include other infertility factors in men and infertility factors in women. 1. Men have other infertility factors: (1) Obstructive azoospermia: e.g. congenital absence of vas deferens, obstruction of vas deferens, etc. (2) Abnormal sexual function: such as insufficient erection caused by physiological or psychological factors, impotence, retrograde ejaculation of semen into the bladder, and so on. (3) Endocrine dysfunction: such as thyroid, adrenal gland, pituitary gland dysfunction affecting sperm production. (4) Immune infertility: male testes, epididymis, vas deferens area barrier is damaged, the formation of their own anti-sperm antibodies. 2. Women have infertility factors: (1) Ovarian dysfunction: ovarian dysfunction leads to persistent non-ovulation. (2) Tubal factors: including tubal inflammation, endometriosis, congenital insufficiency of the fallopian tubes, sterilization and ectopic pregnancy surgery can also cause tubal factors leading to infertility. (3) Uterine factors: including congenital malformation of the uterus, uterine fibroids, endometrial polyps, endometritis, endometrial tuberculosis, uterine adhesions and so on. (4) Cervical factors: including severe cervical erosion, cervical polyps, cervical fibroids and so on. (5) immune infertility: female humoral immune abnormalities, the formation of serum anti-sperm antibodies. Sperm normal infertility may also be related to other factors, it is recommended to visit the hospital in time to check and clarify the cause of the disease and follow the doctor’s instructions to deal with treatment.