A liver-occupying lesion is not necessarily liver cancer. Hepatic space-occupying lesions mainly refer to masses in the liver, including benign tumors and malignant tumors. Hepatocellular carcinoma is a kind of malignant tumor, so there is a certain chance that locoregional lesions of the liver may be hepatocellular carcinoma. However, space-occupying lesions may not always be liver cancer, but may also be a benign tumor. In this case, enhanced CT or magnetic resonance is usually chosen to clarify the cause of the disease, and puncture biopsy can also be used for pathologic diagnosis to confirm whether it is cancerous and the type of cancerous lesion. If liver cancer is diagnosed, early surgical treatment should be performed. In the presence of liver space-occupying lesions, examination should be carried out under the guidance of professional doctors to clarify the cause of the disease and adopt correct treatment to promote the recovery of the disease.