Blood is collected from the soles of the feet of newborns to detect abnormalities in thyroid function, but the probability of the disease is relatively low. Blood collection from the soles of the feet of newborns can be used to determine the presence of hyperthyroidism or hypothyroidism through the measurement of free thyroid hormone, thyroid stimulating hormone and other indicators. In general, the probability of abnormal thyroid function in newborns is relatively low, but there are no clear statistics. Prompt intervention is needed when abnormalities are detected. If abnormal thyroid function is detected after blood is collected from the soles of the feet during the examination of the newborn, prompt medical attention is needed, and parents should actively cooperate with the doctor for treatment to promote the healthy development of the newborn.