Muscle aches and pains in the calves and arms may be caused by muscle fatigue or strain, inflammation, cervical spondylosis or lumbar disc herniation. It is recommended to consult relevant professionals for symptomatic treatment. 1. Muscle fatigue: mostly seen in manual laborers, long-term sports enthusiasts, there is excessive accumulation of lactic acid in the body. It may then lead to calf arm muscle soreness. 2. Strain: Excessive exercise, or exercise posture caused by muscle strain, etc. will cause soreness. 3. Inflammation: commonly caused by infections of the upper respiratory tract. It may cause inflammation to invade the muscles of the calves and arms, which may cause the muscles of the calves and arms to become sore and weak. 4. Cervical spondylosis or lumbar disc herniation: Cervical spondylosis or lumbar disc herniation will compress the nerves, which will lead to soreness and numbness in the calf and arm muscles. There are many other possible causes of calf and arm muscle pain, and it is recommended that when rest does not relieve the pain, timely medical examination and targeted treatment.