Gluteal Epithelial Nerve Entrapment Syndrome needs to be treated with local medication and oral medication, involving drugs such as lidocaine, aspirin, methylcobalamin and so on. 1. Local medication: the condition is controlled by a specialist through ultrasound-guided localization and injection of a mixture of lidocaine and hormones, which can be repeated, but not more than three times. 2. Oral medication: Under the guidance of the doctor, non-steroidal anti-inflammatory drugs such as aspirin, sodium salicylate, etc., pain medication such as ibuprofen, etc. to relieve pain, and also oral vitamin B12, methylcobalamin and other neurotrophic drugs, to alleviate the symptoms of nerve damage. Suffering from superior gluteal cutaneous nerve entrapment syndrome should pay attention to keep warm, avoiding cold aggravate the spasm of the nerve symptoms lead to pain aggravation, can use warm water bag or hot towel on the upper part of the buttocks of the hot compresses, relieve pain and numbness.