Gallbladder stone 3.4cm, in terms of size, has reached the indication of surgical treatment, so for this kind of patients, the first thing that will be recommended is to carry out surgical treatment, also can choose gallbladder drainage. 1. Surgical treatment: Currently, the preferred surgical method is laparoscopic cholecystectomy, which is recommended to be performed within 3 days for patients with acute cholecystitis attacks. If the patient has the following indications, choledochotomy should also be performed at the same time: cholangitis and jaundice before surgery; imaging tests suggest that the patient has choledochal stones, tumors, parasites and other lesions; choledochal diameter > 1cm. 2. Gallbladder drainage: it is suitable for some elderly patients with more comorbidities and difficult conditions who need emergency surgery. The commonly used method is percutaneous gallbladder puncture drainage. When the patient’s gallbladder inflammation subsides, the basic physical conditions improve and then elective cholecystectomy treatment. For patients diagnosed with gallbladder stones, they should go to the relevant departments of regular hospitals and be treated under the guidance of specialized physicians, so as to avoid delaying the condition and causing adverse consequences.