As we enter the fall, there is a significant increase in the number of patients suffering from shingles. This disease, commonly known as herpes zoster, was originally prevalent in the middle-aged and elderly, but is now trending younger, especially in young people in their 20s and 30s. Herpes zoster is caused by the varicella zoster virus and is a unilateral, band-like rash that is distributed along the peripheral nerves. Most patients first present with weeks or days of unexplained pain, followed by flaky erythema in the painful area over which clusters of blisters appear. The virus invades the spinal nerves or cerebral ganglia directly, and patients often suffer from unbearable pain. This disease is associated with decreased resistance and is more frequent in spring and autumn. Now that it is autumn, the weather is dry, the temperature difference between day and night is large, and young people are busy and stressed and do not pay attention to health care in general, which can easily provide opportunities for viral invasion. The best time to treat shingles is within 3 days of the onset of the disease. If treatment is delayed, the damage to the nerves caused by the virus will increase. Even if the virus is completely cleared, it may leave a painful sequelae known as post-herpetic neuralgia. It is important to note that some patients with shingles do not develop skin symptoms in the early stages. Therefore, if localized nerve pain suddenly appears on one side of the body in the absence of trauma or other diseases and lasts for more than a week, be alert to shingles.