Excessive estrogen can cause the following symptoms: 1. Women: It affects women’s menstrual cycle. Estrogen has the function of causing the endometrial glands and interstitium to proliferate, and excessive estrogen can cause the endometrium to continue to proliferate and affect the normal shedding of the endometrium, thus affecting women’s menstrual cycle. Patients have abnormal ovulation, which may affect pregnancy, endometrial thickening and uterine fibroids, etc. 2. Men: Excessive estrogen in men’s bodies It is common in patients with severe liver disease. When liver function is severely damaged, estrogen inactivation is impaired, resulting in elevated estrogen levels in the body, which can lead to male feminization, with patients showing thin voice and breast development, as well as erectile dysfunction, leading to infertility, etc. Estrogen is a substance that promotes the development of female secondary sexual characteristics and the maturation of sexual organs, and is produced by the female ovaries and placenta. Estrogen has a wide and important physiological role in promoting and maintaining the female reproductive organs and secondary sexual characteristics, and has significant effects on endocrine, cardiovascular, metabolic system, growth and maturation of bones, and skin.