High estrogen is related to various factors such as diet, work and rest, and disease. At this time, patients can reduce estrogen in their bodies through diet or medication, and pay attention to timely physical examination to exclude or treat the primary disease. High estrogen is usually caused by excessive stress, unhealthy lifestyle and excessive intake of estrogen. Patients can improve their lifestyle, pay attention to regular living, reasonable diet, regulate their emotions, reduce the intake of estrogen, eat less of foods with high estrogen content such as beans and soy products and onions, and gradually suspend the use of estrogen drugs under the guidance of a doctor. Estrogen is mainly produced by the ovaries, partially secreted by the breasts, liver and adrenal cortex, and regulated by the hypothalamus and pituitary gland, and if the above organs are damaged or infiltrated by tumors, it can also trigger excessive estrogen. Among female patients, liver failure, abnormal ovarian function and uterine fibroids are common, resulting in symptoms such as irregular menstruation, weight gain, weakness and infertility, which should be treated promptly and operated if necessary; in male patients, abnormal liver and kidney function and testicular lesions are common, which are prone to symptoms such as weakness, breast enlargement and decreased sperm quality, which should be treated promptly with liver protection or consultation in male medicine and operated if necessary.