Fracture of the anterior fossa of the skull belongs to a kind of craniocerebral injury, which is mainly manifested by hemorrhage or cerebrospinal fluid leakage from the nose, mouth and eyelids. Nursing care: first, we must closely observe the vital signs and conscious pupil, anterior cranial fossa fracture indicates that the head has suffered a serious impact injury, and delayed cerebral hemorrhage can occur in the later stage, so we must closely observe the mental state, pupil, etc.; if cerebral hemorrhage leads to intracranial pressure, there will be changes in the vital signs such as mental state and pupil, etc.; second, the cavity must be cleaned up, to avoid the cavity from being blocked, and the nostril can be blocked by blood crusts easily, which leads to poor drainage of cerebrospinal fluid. The nostrils are easily blocked by blood crusts, leading to cerebrospinal fluid drainage is not smooth, and intracranial infections may occur; in addition, if the eyelids are extremely bruised and swollen, and the eyes can not be opened, the eyelids must be cleaned or eye drops; the oral cavity must be observed to ensure that the patient’s respiratory tract has no obstruction, especially in patients who are not very clear consciousness, the cerebrospinal fluid caused by misinhalation and respiratory obstruction, respiratory distress or aspiration pneumonia and other conditions.