Indigenous methods of treating toothache are unreliable, you should choose the scientific and correct method to treat toothache. Toothache may be caused by pulpitis, periapical inflammation, wisdom tooth periapical inflammation, oral malignant tumors, and can be treated by root canal therapy, oral ibuprofen, surgery and other ways. 1. Pulpitis, periapical inflammation: often due to dental caries leading to inflammation of the pulp, the pulp is stimulated by inflammation and cause pain, feasible root canal treatment to remove the infected foci in the pulp can relieve toothache. 2. Wisdom tooth pericoronitis: due to food inlay causes wisdom tooth pericoronitis, you can take oral ibuprofen, aspirin and other drugs to relieve pain, with the taking of amoxicillin, cephalexin and other antibacterial drugs to prevent and control infections, the inflammation can be removed after control of wisdom teeth. 3. Oral malignant tumors: oral malignant tumors grow close to the tooth bed, can lead to toothache, can be surgically resected tumors, with radiotherapy, chemotherapy and other means of treatment. Toothache should go to the regular medical institutions in time, improve the examination, clear the cause of the disease and then targeted treatment, the use of drugs need to follow the doctor’s instructions.