A strong dry cough at night should be treated with appropriate medication according to the cause of the dry cough, which is more commonly known as acute bronchitis, pneumonia, allergic cough and so on. 1. Acute bronchitis, pneumonia: when bacteria, viruses, mycoplasma and other infections of the bronchial mucosa or lungs, the patient may have a strong dry cough at night, if it is a severe dry cough, affecting daily life, you can use cough suppressants to improve the symptoms, such as dextromethorphan, Pentoxifylline, phenylpropylphenidate and so on. If it is clear that there is a bacterial infection, you can choose antibiotic drugs, such as cefixime, amoxicillin and so on. If there is mycoplasma infection, azithromycin, levofloxacin and other anti-infective treatment can be given. 2. Allergic cough: the pathogenesis and etiology of allergic cough is not particularly clear, mainly manifested as paroxysmal irritating dry cough, you can use dextromethorphan, codeine, etc., the serious short-term use of glucocorticoid drugs, such as prednisone, methylprednisolone, and at the same time, the use of loratadine, cetirizine and other anti-allergic drugs. Dry cough at night, may also be seen in cough variant asthma, acute and chronic pharyngolaryngitis, drug-induced cough, etc., if the cough is serious, you should go to the hospital in a timely manner to identify the cause of the symptomatic treatment, and if you need to use medication, you should strictly comply with the doctor’s instructions.