RHC positivity indicates that the subject has Rh-positive blood with antigens present on their red blood cells, while in contrast RHE negativity indicates that antigens are not present on their red blood cells. In human blood, red blood cells make up 99% of the total blood cells. On the surface of the erythrocyte membrane, there are various specific antigens called blood group antigens. Blood group antigens mediate antigen-antibody agglutination, and different antigens carried on the surface of red blood cells can distinguish different blood groups. When blood that does not match the patient’s blood type is injected into the patient’s body, red blood cell agglutination occurs in the blood vessels, and hemolysis occurs under the action of complement, which can be life-threatening in severe cases. The RH blood group system is the more complex of the red blood cell blood groups, with more than 40 known Rh antigens, and RHE-negative means that there are no Rh antigens on the red blood cell membranes. It is recommended that due to the fact that RHE-negative patients have fewer blood types, they are commonly known as panda blood. Therefore, trauma should be avoided in daily life. This is due to the fact that when a blood transfusion is needed, the hospital reserve may have less of this blood type, resulting in inducing other complications.