The most common cause of anal itching with blood on the paper after stool is due to anal pruritus. The main manifestation is paroxysmal pruritus around the anus, some patients can be accompanied by pain, and early itching is obvious at night. The symptoms can be aggravated after eating a spicy diet, drinking alcohol, getting cold, or sitting for a long time, and can be relieved by applying anti-allergy ointment treatment. Longer duration of the disease can be localized skin ulceration, exudation, crusting, can appear blood on the stool paper phenomenon. The main treatment is to actively remove the causative factors, and can be treated with topical application of glyburide lotion and oral antihistamines. It is also common in perianal eczema and itchy, acute perianal papules, long duration of the disease, skin hypertrophy, can appear perianal fissure caused by bleeding during stool. You can apply 10% calcium gluconate injection, slow intravenous injection or intravenous drip, oral loratadine and other treatment.