Hard lumps on the buttocks may be subcutaneous lipomas, fibromas, sebaceous cysts, cutaneous papillomas, skin scars, and so on. These conditions will not be eliminated by medication, physical therapy and other measures, and require surgical removal. Subcutaneous lipoma, fibroma, sebaceous cyst, skin papilloma are benign skin tumors of the skin, slow-growing, small impact on the human body, such as no obvious discomfort, can be observed, do not need any treatment; if due to the size of the larger, the appearance of pressure on the surrounding tissues, or to affect the aesthetics, can be considered for surgical excision, postoperative specimens routinely sent to pathology biopsy. In addition, buttock skin folliculitis, carbuncle, etc. may also cause hard lumps, can be given topical mupirocin ointment, erythromycin ointment, and take amoxicillin, cefaclor and other antibiotics, the formation of abscess can be treated with surgical incision and drainage. Drugs should be applied under the guidance of a doctor.