It is possible to have intercourse on the day of the HPV shot, but you should be careful to use contraception. Sex will not affect the effect of the HPV vaccine, so you can follow the original frequency of sex, no need to deliberately control or prohibit sex. However, since the HPV vaccination requires three injections, pregnancy is not recommended during this period if the entire course is not completed, so it is very necessary to take contraceptive measures; if you have already completed three injections of HPV vaccine, pregnancy is not recommended within a short period of time. Therefore, it is possible to have intercourse on the day of HPV vaccination, but it is important to take precautions to prevent pregnancy. If you need to prepare for pregnancy, you need to do so under the guidance of a professional doctor.