Causes of long-term edema in the elderly include chronic cardiac failure, hypoproteinemia, and medication-based edema, etc. In the absence of eradication of the causes of the disease, it is difficult for edema to disappear on its own. 1. Chronic heart failure: The structure and function of the heart are changed due to various reasons, which finally cause low blood supply and filling function of the heart, and then lead to fluid retention, and edema will be formed. The main therapeutic measures for this condition are to improve the symptoms, quality of life and slow down the progression of the disease, so edema may persist for a long time or recur. 2. Hypoproteinemia: When hypoproteinemia occurs due to infection, severe anemia, liver disease, or kidney disease, the elderly may experience generalized edema, which will persist until the cause is eradicated. 3. Pharmacogenic edema: edema caused by long-term use of certain drugs is generally an adverse reaction to drugs. When the drug is not stopped, the edema phenomenon will still persist. Because of the influence of more factors, so the elderly edema phenomenon is more difficult to disappear on their own, but must be timely consultation, and under the guidance of the doctor for standardized treatment.