In the middle of the night, sudden stomach pain and drooling consider the possible existence of duodenal ulcer, gastritis and so on. 1. duodenal ulcer: refers to the duodenum itself is digested by gastric acid, pepsin, etc., the formation of localized inflammatory defects, abdominal pain occurs in the night when hungry, food is digested at night, gastric acid directly on the duodenal mucosa, due to mucosal stimulation and symptoms of pain. 2. Gastritis: a long time of irregular diet can lead to inflammatory lesions in the mucosa of the stomach, the acute stage of inflammation, gastric acid secretion, can appear in the middle of the night regiment of stomach pain symptoms, can also be accompanied by nausea, vomiting and other symptoms. Sudden stomach pain in the middle of the night drooling can also be caused by other reasons, it is recommended that patients go to the hospital in a timely manner, perfect gastroscopy and other auxiliary examination, clear condition, targeted treatment.