Sore and uncomfortable legs may be caused by muscle strain, herniated lumbar disc, osteoporosis or varicose veins. Depending on the situation, general treatment, medication and surgery can be taken to relieve the pain. 1. Muscle strain: Strenuous running and jumping exercises cause muscle strain and local lactic acid accumulation, which causes leg swelling and acidity, can be relieved by massage and rest, thus reducing the discomfort of the calf. 2. Lumbar disc herniation: The compression of nerves due to lumbar disc herniation causes soreness and swelling of the calves. Patients can take non-steroidal anti-inflammatory drugs to eliminate sterile inflammation, such as ibuprofen, etc., which can inhibit prostaglandin synthesis and relieve leg discomfort. If necessary, medullary nucleus removal surgery, nerve release surgery and other treatments. 3. Osteoporosis: Calcium deficiency in osteoporosis can cause cramps in the calf muscles and induce soreness in the calves. It is recommended to consume more calcium-rich and protein-rich foods, such as milk and nuts, in your daily diet. Protein is the material that makes up the bone matrix, and high calcium intake is very beneficial for osteoporosis. 4. Varicose veins: Varicose veins lead to soreness and swelling in the legs, and you can also see obvious blood vessel tortuosity in the legs. Oral calcium hydroxybenzenesulfonate capsule, Diosmin tablets and other drugs can be used to improve the venous return of the lower limbs, promote venous edema, and promote local microcirculation. If necessary, the saphenous vein high knot or tie varicose vein stripping surgery. There are other reasons for leg soreness and swelling, and it is recommended to go to the hospital in time. The above drugs need to be standardized under the guidance of a doctor to avoid adverse effects.