Biliary reflux gastritis with erosion is a chronic inflammatory disease caused by dysfunction of the pyloric sphincter or pyloric surgery, resulting in the flow of duodenal contents containing bile and pancreatic juice into the gastric lumen, causing inflammation, erosion and bleeding of the gastric mucosa. Patients often present with abdominal fullness and discomfort, persistent burning sensation in the middle and upper abdomen, belching, acid reflux, nausea, vomiting, and loss of appetite. Patients can use domperidone and mosapride to increase gastrointestinal peristalsis and inhibit the regurgitation of bile into the stomach under the guidance of a physician. In addition, drugs such as ranitidine, famotidine and omeprazole can inhibit gastric acid secretion and protect the gastric mucosa. For bile reflux gastritis with H. pylori infection, quadruple eradication therapy can be performed, which not only facilitates the healing of lesions but also reduces the chance of carcinogenesis. Patients with bile reflux gastritis with erosion should develop good dietary habits, quit smoking and drinking, avoid strong tea and coffee, avoid cold and spicy foods, and eat more fresh vegetables and fruits. Keep your mood relaxed, pay attention to rest, exercise properly and enhance your physical fitness.