Ezetimibe mainly blocks the absorption of cholesterol in the intestines and acts as a cholesterol-lowering agent. There are three main sources of cholesterol in our body: First, the liver utilizes some raw materials in our body to re-synthesize cholesterol from scratch. Second, after cholesterol is excreted into the bile, it enters the intestines, where it is then reabsorbed into the blood. Third, cholesterol in food, such as cholesterol from egg yolks and liver, can also be absorbed by the intestines into the blood to form cholesterol in our body. Ezetimibe mainly inhibits the absorption of cholesterol in the intestines, such as cholesterol from bile or cholesterol from food, and its absorption can be prevented and reduced by Ezetimibe. Therefore, ezetimibe is mainly used as an inhibitor of exogenous cholesterol absorption, which can reduce the level of cholesterol in our body, and in combination with statins, it can prevent the increase of serum cholesterol level from both endogenous synthesis and exogenous absorption, which may have a synergistic effect.