CIN grade 2 has a 5% to 10% chance of developing into invasive carcinoma within ten years. CIN2 grade refers to heteroproliferative cells involving the lower 1/3~2/3 of the epithelial layer, most of which are accompanied by high-risk HPV infection. If not actively treated, it can gradually develop into CIN3 grade until invasive carcinoma or directly invasive carcinoma. Therefore, CIN2 grade requires timely intervention and treatment, and the treatment method is chosen according to whether the patient has reproductive needs and the patient’s age. Younger women who have not yet had children can choose laser and cryotherapy as well as small-scale cervical conization based on adequate colposcopic examination, while older women with high-risk HPV infection who do not have childbearing needs can undergo large-scale cervical conization or hysterectomy. For patients with CIN2 grade, they should be examined and treated in a timely manner to prevent further development of the lesion into cancer. During treatment, patients with CIN grade 2 should prohibit sexual intercourse and avoid eating stimulating and spicy food. After treatment, follow-up examination is conducted to detect whether the lesion has continued to develop.