The main reasons for epiphyseal closure are as follows: 1. Physiological reasons, after the growth and development of the human body gradually tends to stop, the epiphysis will gradually ossify and close, at which time the long bones lose the ability to continue to grow, and the human height is basically fixed. 2. Epiphyseal closure may be caused by injuries related to the epiphysis, for example, during the growth and development period, if the patient’s epiphysis suffers a For example, during the growth period, if the epiphysis suffers a direct violent blow or an injury to the epiphysis due to a fracture or dislocation, this may directly lead to ossification of the epiphysis or osteophytes such as bone bridges, which may induce the gradual closure of the local or total epiphysis. 3, it may be caused by local infection, for example, when the patient develops acute septic osteomyelitis or intra-articular infection, this may lead to the gradual closure of the adjacent epiphysis. 4. It may be caused by local inflammation, such as overexertion or excessive compression of the bone around the epiphysis, which may lead to aseptic inflammation around the epiphysis and gradual closure of the epiphysis.