Slightly low average hemoglobin concentration means that the amount of hemoglobin in each red blood cell is not at the normal level, and may be associated with anemia, diseases of the liver, etc., as well as hematopoietic abnormalities. Hemoglobin is the main part of the red blood cells that performs the function of transporting oxygen and carbon dioxide, and when the average hemoglobin level decreases, the function of the red blood cells is also affected. 1. When the number of red blood cells as well as the total hemoglobin level is lower than normal, it may be due to blood loss anemia. 2. Hemoglobin needs to be synthesized by the liver. When the liver is diseased (e.g., hepatitis, etc.), the ability to synthesize it is reduced, and a mildly low average hemoglobin concentration may also occur. 3. In addition, abnormal hematopoietic function can also lead to slightly low average hemoglobin concentration, including acute leukemia, aplastic anemia, thalassemia, and iron deficiency anemia. For patients who are found to have a slightly low average hemoglobin concentration, it is recommended that they undergo further examination under the guidance of a physician to clarify the specific cause.