Patients with anal fistula have their own personal experience and pain. Once the fistula is formed, there is little chance of self-healing, and the fistula is complicated, which brings many troubles and certain harm. The first thing you need to do is to get a good idea of what you are getting into. 2.Long time without proper treatment will make the body weak or thin, mental discomfort, and weaken the ability to resist disease. 3, due to repeated episodes, pus can penetrate the wall of the tube along the sphincter gap spread and form multiple, complex anal fistula, not only bring difficulties to treatment, but also affect the normal physiological function of the anus. 4, the multiplicity of anal fistula, can form a rectovaginal fistula or rectal bladder fistula, endangering the surrounding organs. 5, due to the long period of chronic stimulation, over time, the anal fistula will have a tendency to malignant change.