Bones are the scaffolding of the body and produce the vital tissues that involve human movement. Although bones make up an important part of the body and can be seen on almost every x-ray, bone cancer is rarely found inadvertently. The skeletal system, like other organs, can develop tumors from any tissue component or metastatic lesions from other organs. Tumors that invade the bones can be called benign tumors if they are benign, or cancer if they are malignant. The initial symptoms of bone cancer are not very obvious, specifically the following. So, what are the symptoms of bone cancer? Pain is the main symptom of bone tumor in early stage, which is mild and intermittent at the beginning of the disease, but with the progress of the disease, the pain can gradually increase and develop into continuous. Most of the patients’ pain increases at night and affects their sleep. The pain can be radiated to distant places. 2. Swelling or lump Tumor located under the periosteum or superficially appears earlier, and the bone can be swollen and deformed by touch. If the tumor penetrates outside the bone, it may produce a fixed soft tissue mass with smooth or uneven surface. 3.Dysfunction When bone cancer patients are in the late stage, some functions of patients will be impaired due to pain and swelling, and there will be corresponding muscle atrophy symptoms. 4.Compression symptoms Tumors growing into the cranial cavity and nasal cavity can compress the brain and nasal tissues, resulting in cranial pressure and poor breathing; pelvic tumors can compress the rectum and bladder, resulting in difficulty in defecation and urination; spinal tumors can compress the spinal cord, resulting in paralysis.