After the end of puberty, the possibility of breasts developing again is relatively small, and it is not recommended to use drugs to enhance breasts to avoid affecting the level of hormones in the body. During puberty, the secondary sexual characteristics begin to develop, the mammary glands are affected by the hormone levels in the body, the development of enlargement, nipples, areolas begin to hyperpigmentation. At this time, pay more attention to supplemental nutrition, and develop a good habit of life and work, to promote the development of mammary glands. Once the end of puberty mammary gland stops developing, the possibility of breast enlargement again is very small, after 30 years of age mammary gland development has ended, can not be developed again, you can usually pay more attention to the upper limbs and chest exercise, you can play a very good shaping effect. At present, the only effective method of breast enlargement is through surgical treatment, more safe and reliable is the autologous fat filling surgery, this surgery is permanent, there will not be a reaction, it is recommended to the regular hospital breast department consultation.