Wake up in the morning dry mouth and bitter mouth may be related to periodontitis, fire, dry syndrome and other factors, the cause of different, the solution will also be different. Specifically as follows: 1. Periodontitis: dental calculus on the teeth, plaque and other local stimulation of the gums, which in turn leads to inflammation of the gums, bleeding, may also produce the phenomenon of bitter mouth. For this situation, it is recommended to be treated by scaling and scraping, and usually pay attention to oral hygiene. 2. Fire: Mostly related to liver fire, too much liver fire will lead to bile flowing upwards, resulting in symptoms of dry mouth and bitter mouth. For this situation, it is recommended to take some drugs to clear liver fire, such as gentian liver pill. Diet mainly focuses on light diet, and eat less spicy, deep-fried, fire food. 3. Dry Syndrome: This will lead to a decrease in saliva secretion in the mouth, which in turn leads to symptoms such as dry mouth and bitter mouth. For this situation, you can take some drugs to improve the dry mouth under the guidance of the doctor, such as Pilocarpine, you can also commonly use mouthwash gargle to keep the mouth moist and prevent bacterial growth. If the symptoms of dry mouth and bitter mouth are not relieved, and accompanied by other uncomfortable symptoms, it is recommended to consult a doctor in time.