Scrotal dryness and cracking can be caused by physiological skin dehydration or pathologic fungal infections, especially in diabetic patients who are prone to scrotal skin dryness and cracking. Different situations need to be treated differently. If the scrotum dry crack is simply caused by skin dehydration, then you need to wash with water every day, and drink more water. If the scrotum dry crack is caused by fungal or bacterial infection, then usually need to disinfect with iodophor and take erythromycin enteric-coated tablets, tetracycline, and ofloxacin internally. Patients can also wash with 3% boric acid lotion. If a diabetic patient has dry and cracked scrotal skin or even ulceration, he needs to actively control his blood sugar. If accompanied by infection, under the guidance of the doctor, oral antibiotics corresponding to the causative bacteria for treatment. Patients who find that their scrotum is dry and cracked should go to a regular medical institution for evaluation and treatment. Use medications as prescribed.