Taking medication without eating can easily cause gastrointestinal reactions and increase the likelihood of suffering from digestive disorders in the long run. When taking medication, you need to know in detail how to use the medication and choose to take it before or after meals according to the instructions. There are some drugs that need to be taken before meals, such as omeprazole and mosapride, which are normal when taken without meals and will not affect the effect of the drug. But there are some drugs, taken without eating, will cause greater stimulation of the mucosa of the stomach wall, such as metformin, aspirin, chemotherapy drugs, etc. Often eat these drugs in the state without eating, the composition of the drug will cause stimulation of the gastric mucosa, will cause nausea, vomiting and other gastrointestinal reactions, long-term will be more likely to suffer from gastritis, gastric ulcer, duodenal ulcer and other diseases.