There is no most effective way to stop coughing at night, children’s cough at night may be caused by environmental dryness, allergic cough, gastroesophageal reflux, etc., and need to be targeted to take the general treatment, drug treatment. 1. environmental dryness: when children live in a dry environment can appear at night cough, usually mild cough, no progressive aggravation, parents need to pay attention to maintain a certain degree of indoor temperature and humidity, change the triggers, cough can be relieved. 2. Allergic cough: first of all, we have to look for allergens, such as pollen, animal dander, etc., and avoid exposing children to them, and if necessary, take oral anti-allergy drugs, such as cetirizine hydrochloride and loratadine. 3. Gastroesophageal reflux: prohibit water intake 2 hours before going to bed at night, usually take thick and thick food as the main, and raise the upper body appropriately when sleeping, and give the children acid-suppressing drugs and gastric stimulating drugs, such as omeprazole, rabeprazole, moxapride, domperidone and so on. All of the above medications should be used under the guidance of a doctor, and avoid self-medication. Coughing at night may also be caused by other reasons, and should be treated in a timely manner in the hospital and evaluated by a specialist.