The increasing number of patients with retinal detachment may be related to the variety of current screening methods and the increased attention paid by patients themselves. Primary retinal detachment (also known as foraminogenic retinal detachment) must be treated surgically, and secondary retinal detachment, most of them also need surgery, and the earlier the timing of surgery, the better, and the prognosis for surgery more than 3 months later is poor. Often patients with retinal detachment go to the hospital half a year or even one or two years after the onset of the disease, thus missing the best time for treatment. According to clinical statistics, early retinal detachment mostly has no special sensation, and careful patients can sometimes recall a history of concussion in the eye or head. At present, early retinal detachment can be treated by laser, but if retinal detachment occurs, it needs to be treated by surgery. The best option for treating retinal detachment is biosurgery. There are many indications for biosurgery, including: indications for the anterior segment, such as soft cataracts, pupillary membranes, perforated injuries to the anterior segment, lens detachment in the anterior chamber, vitreous corneal contact syndrome, and malignant glaucoma. It is also indicated for diseases related to the posterior segment of the eye, such as vitreous hemorrhage, intraocular foreign body, endophthalmitis, retinal detachment, and crystal dislocation into the vitreous. Minimally invasive biosurgery can treat the following retinal detachments: 1. Proliferative vitreoretinal lesions retinal detachment. Proliferative vitreoretinal lesions are the main cause of failed retinal detachment repositioning surgery. This lesion often occurs after long-term, old detached retina, intraocular inflammation, retinal detachment with vitreous hemorrhage, giant fissures, multiple failed retinal detachment repositioning surgeries or excessive retinal electrocoagulation and condensation. 2.Traction retinal detachment. It is often caused by ocular trauma and retinal vascular disease. Vitrectomy is the best surgical procedure for traction retinal detachment. 3, retinal stiffness or traction retinal detachment of posterior pole hole origin. This kind of retinal detachment is complex, difficult to operate conventionally, and easy to damage the optic nerve and macula. It can be treated by vitrectomy combined with gas or silicone oil filling. 4.Recurrent retinal detachment. Due to the failure of repeated conventional retinal detachment repositioning surgery or vitrectomy, it leads to severe vitreoretinal lesions with many fixed retinal folds, rigid retina and reduced mobility. Therefore, vitrectomy and vitreous filling combined with scleral ring ligation was required.