Couples with chromosomal disqualification are not recommended to have children, because even if they get pregnant they will be prone to miscarriage and premature birth, which will bring a great psychological burden to both spouses. If you want to have a child, you can do IVF, which is a combination of sperm and eggs of good quality, to avoid miscarriage and premature birth, and the possibility of having a healthy baby, but the cost will be relatively high, it is recommended to go to a specialized infertility hospital for treatment, do not blindly treat, so as not to delay the best time to have a child. It is recommended to do detailed prenatal checkups after pregnancy, and it is recommended to do amniotic fluid chromosome examination at 16-20 weeks, and if there is any abnormality, it is necessary to terminate the pregnancy in time to ensure the birth of a healthy baby.