Human papillomavirus HPV negative is a good sign that there is no HPV infection in the cervix or vagina according to current screening methods. There are many types of human papillomavirus, more than 100 types have been found so far, and they are artificially categorized into low-risk and high-risk types according to their pathogenicity. Infection with low-risk types of HPV is associated with the development of genital warts. In contrast, persistent infection with high-risk types of HPV is related to the development of cervical cancer, which is why screening for HPV is so important. After having sex, regular HPV screening can detect cervical lesions early and take effective treatment in time. At the same time, strengthening the body’s resistance can remove the HPV virus in time, thus preventing the further progress of cervical lesions.