Soreness and generalized weakness are considered to be related to physiological factors such as strenuous exercise and heavy drinking, as well as upper respiratory tract infection and polymyositis. 1. Physiological factors: for the recent strenuous exercise, drinking a lot of alcohol, overwork, mental overstress, prone to body aches and general weakness phenomenon. 2. Upper respiratory tract infection: the disease is related to viral and bacterial infections, while overwork and decreased immunity are the triggering factors. Upper respiratory tract infections can cause some patients to experience body aches and generalized weakness, accompanied by sneezing, runny nose, chills, fever and other discomforts. 3. Polymyositis: the cause of the disease is not yet clear, may be related to autoimmunity, genetic factors, environmental factors. Patients may have symmetrical progressive weakness of the proximal muscles of the limbs, dysphagia, choking on drinking water, etc., and may also have body aches and generalized weakness. In addition, low blood potassium, anemia, etc. can cause body aches and weakness, and it is recommended that patients seek medical treatment in time.