Symptoms that occur in advanced cirrhosis include gastrointestinal bleeding, hepatic encephalopathy, and hypoproteinemia. The treatment methods are different depending on the symptoms. Commonly used treatments include medication, surgery, puncture tube placement and so on. 1. Gastrointestinal bleeding: The symptoms of gastrointestinal bleeding are triggered by the rupture and bleeding of esophagogastric fundus varices or hemorrhoidal varices. Surgery can be chosen to improve the symptoms, such as endoscopic hemostasis, splenectomy, portal vein shunt and so on. 2. Hepatic encephalopathy: Due to high blood ammonia in the patient’s blood, the patient may suffer from behavioral disorders, consciousness disorders, cognitive disorders, disorientation disorders and other mental symptoms. Symptoms can be improved by medication, such as lactulose and Mentholatum ornithine, to promote excretion, remove blood ammonia from the blood, and reduce the level of blood ammonia in the human body. 3. Hypoproteinemia: As the nutrition of patients with advanced cirrhosis can not keep up, the liver and kidney function decreases, resulting in hypoproteinemia, which triggers the patients to have ascites, generalized edema and other symptoms. Ascites can be drained by ultrasonic tube placement. Diuretic drugs such as furosemide and spironolactone can be used to promote urine discharge and improve symptoms. In addition to the above treatments, advanced cirrhosis should also be treated according to different specific conditions of patients. If the patient is in advanced cirrhosis, it is recommended that the patient go to the hospital in time. Improve the relevant examination and follow the doctor’s instructions for treatment, so as not to aggravate the condition and cause adverse consequences.