Congenital anogenital anus, also known as congenital anal atresia, is mostly caused by the lack of development of the genitourinary system due to unexplained effects on the genitourinary or rectal system during embryonic development. Congenital anogenital atresia may be caused by drugs that affect the fetus during maternal development or drugs that have an effect on the fetal genitourinary system, resulting in abnormal mutations and translocations of certain fetal genetic fragments and chromosomes that affect the normal development of the fetal genitourinary and reproductive systems. This condition can also occur if there is a family history of anorectal or rectal anorectal disease, maternal endocrine disorders, etc.