Bladder papillary tumors usually refer to papillary tumors of the bladder, which usually do not cause yellowing of the sclera or gastric upset. Bladder papilloma is usually a low malignant potential papillary uroepithelial tumor with normal cell morphology and no cytologic features of malignancy. Although the risk of progression of this tumor is minimal, it is not entirely a benign lesion and is still subject to recurrence. The main clinical manifestation of papilloma of the bladder is painless hematuria of the naked eye, which may also be accompanied by urinary frequency, urgency, and pain. Scleral yellowing and stomach discomfort are most commonly associated with diseases of the liver or gallbladder, such as cirrhosis, hepatitis, cholecystitis, and gallbladder stones. If jaundice will be caused by liver and gallbladder diseases, it can be manifested as yellowing of skin or sclera. Moreover, liver and gallbladder belong to digestive system diseases, and gastrointestinal symptoms are often present at the onset. If the bladder tumor is in advanced stage and has metastasis, such as metastasis to the liver and digestive system, jaundice and digestive discomfort may occur, but it is relatively rare. If there is any discomfort, suspected or diagnosed as papillary bladder tumor, it is recommended to go to the regular hospital for comprehensive assessment of the condition, follow the doctor’s instructions to cooperate with the treatment, choose the appropriate treatment plan to improve the patient’s prognosis, so as to avoid delaying the condition.